Nanofat can restore and revitalize your skin to a healthier, more youthful appearance.The fat’s regenerative components can be injected to improve the appearance of scars, uneven skin tones, and other similar skin issues.

Home / Nanofat Injections: Next Generation Facial Volumization and Rejuvenation


Cosmetic procedures use different types of fat for different procedures. These fats vary in extraction methods and their utility when injected. Dr. Fred Coville has been using three types of fat for many years in his Cornerstone Plastic Surgery practice. The main types of fat we use include macrofat, microfat, and nanofat.

Macrofat is typically required for large volume procedures, like the Jersey Shore Brazilian Butt Lift. To achieve the shape and size you desire, we transfer a bigger quantity of fat harvested through larger cannulas from donor sites like the abdomen or waist. These large fat globules are lightly processed to remove fluid and damaged cells before they’re injected into the targeted area. Macrofat can be used wherever larger volumes are needed, such as the buttocks or even breasts.

Microfat is employed to increase volume in more delicate areas like the face, lips, and below the eyes. It can also improve small scar depressions or be placed in the labia for feminine rejuvenation procedures. The cannulas collecting microfat are significantly smaller than those for macrofat, with much smaller fat particles being harvested as a result. This microfat is then processed to remove any oils and water before being injected into the treatment area.

Nanofat is microfat that goes through an additional processing step to modify its properties. It’s harvested with even smaller caliber cannulas than microfat. Following extraction, the fat is also purified. Where the two types of fat differ: nanofat undergoes a mechanical process to destroy the fat structure itself, leaving a complex mixture of regenerative cells and other components in the form of a smooth, injectable liquid. That’s nanofat.



Unlike macrofat and microfat, which are primarily injected below the skin to restore volume, nanofat is injected directly into the skin for its regenerative properties, providing a younger, healthier appearance to the treated area. Nanofat injections can be a standalone procedure to:

  • Repair skin damage
  • Even out skin pigmentation
  • Improve skin texture
  • Tighten and rejuvenate tissue

Apart from standalone procedures, injections can also be used alongside other non-surgical options to provide a combination treatment.

The Facial Time Warp, one of our most popular facial rejuvenation procedures, uses nanofat to bolster its revitalizing effects. Facial Time Warps combine microfat, nanofat, and platelet-rich plasma (PRP) injections for a full facial treatment.

During this process, microfat first restores volume to the face, followed by nanofat and PRP using a radiofrequency Morpheus microneedling device. This reinvigorates the skin while addressing scars, uneven skin tone, and other blemishes.

Nanofat is a key component in our non-surgical feminine rejuvenation treatments. Nanofat, microfat, and PRP are injected into the labia to restore volume and tighten lax skin. In addition to the aesthetic improvements, this feminine rejuvenation treatment also enhances sexual function and treats stress incontinence.

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If you’ve noticed a greater prevalence of fine lines and wrinkles, sunken skin around your eyes, dark circles, and other signs of aging to your skin, you may be a great candidate for nanofat injections with Dr. Coville. Be sure to tell the doctor about your medications, smoking status, and the rest of your medical history to receive the maximum benefit of the procedure and Dr. Coville’s expert talents.


Pretreatment preparations and adherence to post-procedure instructions play a vital role in the success of your procedure. Following these simple instructions will ensure your final results are as good as they can possibly be.

The first step of your nanofat injection is meeting with our team. During your complimentary consultation, you will meet Dr. Coville. He will explain the procedure in detail and answer any questions you may have. Together you will explore the options available and draft a customized treatment plan.

On the day of your procedure, you will need to remove any hair from the donor site to facilitate the fat collection process. If you’re prone to cold sores or genital warts around the treatment or donor sites, you’ll need to use the appropriate pretreatment medication in advance of your procedure.

We will apply a topical anesthetic to both the treatment and donor sites to ensure your comfort throughout the procedure. While topical anesthetics are typically used for nanofat treatments, you may also request oral sedatives and nitrous oxide gas.

The first step of the procedure involves removing fat from the donor site using a small caliber cannula. Depending on your body’s natural distribution of fat and your personal preferences, fat is typically collected from the inner thighs, inner knees, lower abdomen, or flanks.

Following extraction, Dr. Coville purifies the fat to remove any damaged cells or additional fluids. The fat is then mechanically processed to emulsify it, leaving a regenerative liquid that is ready to inject. During the final step of this process, nanofat is carefully injected into the tissue at the treatment site. The entire process takes approximately 90 minutes, with patients returning home immediately following treatment.


Why Choose Dr. Coville For My Nanofat Treament?

Successful fat injection procedures require a combination of skill, technique, and experience to ensure comfort throughout the entire process. Dr. Coville conducts every fat injection performed in our New Jersey facilities, and with over 20 years of experience, he’s a master of the process.

Where Is Nanofat Injected?

While skin across the entire body benefits from nanofat injections, the most commonly targeted areas are where the skin is frequently visible, such as the face, hands, and décolleté.

Why Do You Recommend Nanofat Injection?

Nanofat injections rejuvenate both the skin and other tissues. Few procedures can reinvigorate tissue using the body’s restorative properties the way nanofat does.

If you’re living with scars, fine wrinkles, or other blemishes, nanofat is one of the best non-surgical options available. Similarly, the results of these injections are unmatched when it comes to non-surgical vaginal rejuvenation.

Are Nanofat Injections An Effective Form Of Weight Loss?

While it’s true some fat is removed from a donor site to acquire nanofat, only trace amounts are necessary for this procedure. Hence, the tiny amount of fat harvested makes no significant difference to the donor site or its surrounding area.


The recovery process is fairly quick and simple. Mild swelling, bruising, and redness may occur around the injection site; however, these typically fade shortly after the procedure. In some cases, patients may experience mild, localized discomfort once the topical anesthetics wear off.

The procedure requires little downtime. While patients should avoid strenuous activities for up to 1 week, most people can return to work and their normal daily activities within 1-3 days.

Once the recovery process is complete for most patients, the final results take between 3-6 months to become fully apparent. In the months following treatment, patients should slowly begin to notice:

  • Tighter tissue in the treated area
  • A more even skin tone
  • Improvements to skin texture
  • A reduction in scaring and similar blemishes

Patients can expect long-lasting results after only one nanofat treatment. While the injections can’t stop the natural aging process, the improvements provided by the procedure remain apparent for many years.

Written By: Dr. Frederick Coville
Frederick A. Coville, M.D., Cornerstone Plastic Surgery’s Owner and Medical Director


Frederick A. Coville, M.D., Cornerstone Plastic Surgery’s Owner and Medical Director, has been an Aesthetic and Reconstructive Plastic Surgeon for over 25 years. He firmly believes each of us possesses an inner “Foundational Beauty.”

As a student of beauty all his life, he calls upon his naturally artistic eye and God-given talents as a surgeon to deliver the results you demand. Dr. Fred likes to say, “It’s my job to help you find Your Beautiful!”

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